Duración de la lactancia y desarrollo cognitivo.

Breastfeeding Duration and Cognitive Development at 2 and 3 Years of Age in the EDEN Mother–Child Cohort Jonathan Y. Bernard, MScemail address , Maria De Agostini, PhD , Anne Forhan, MPH , Toni Alfaiate, MPH , Mercedes Bonet, PhD , Valérie Champion, MSc , Monique Kaminski, PhD , Blandine de Lauzon-Guillain, PhD , Marie-Aline Charles, MD, PhD , Barbara Heude, PhD , EDEN Mother-Child Cohort Study Group Objective To investigate the dose–response relationship between breastfeeding duration and cognitive development in French preschool children. Study design In the French EDEN Mother–Child Cohort Study, we evaluated language ability with the Communicative Development Inventory (CDI) in 1387 2-year-old children and overall development with the Ages and Stages Questionnaire (ASQ) in 1199 3-year-old children. Assessments were compared between breastfed and non-breastfed children and also according to breastfeeding duration in multivariable linear models, controlling for a wide range of potential confounders. We tested departure from linearity. Results After adjustments, ever-breastfed children scored 3.7 ± 1.8 (P = .038) points higher than never-breastfed children on the CDI and 6.2 ± 1.9 (P = .001) points higher on the ASQ. Among breastfed children, exclusive and any-breastfeeding durations were positively associated with both CDI and ASQ scores. The fine motor domain of ASQ was associated with any-breastfeeding duration, and the problem solving domain with exclusive-breastfeeding duration. We did not observe significant departures from linearity. No interactions were found between the child's sex, parental education or socioeconomic status, and breastfeeding duration. Conclusion Longer breastfeeding duration was associated with better cognitive and motor development in 2- and 3-year-old children and a dose–response relationship was suggested.